Flumazenil is the brand name for which antidote?

• A. Diprivan
• B. Romazicon
• C. Narcan
• D. Mucomyst

Answer: (B)

Flumazenil is the antidote for benzodiazepine overdose because it is a competitive antagonist at the benzodiazepine binding site on the GABA-A receptor, rapidly reversing sedation and respiratory depression produced by benzodiazepines such as diazepam, lorazepam, and midazolam. The brand name for this antidote is Romazicon, which is why that option is correct.

The other drugs listed are different agents with distinct roles: Diprivan is propofol, Narcan (naloxone) reverses opioid effects, and Mucomyst (acetylcysteine) is used for acetaminophen overdose. Keep in mind flumazenil’s effects can wear off before a long-acting benzodiazepine is cleared, so re-sedation can occur and patients must be monitored closely. It’s also used with caution in chronic benzodiazepine users due to withdrawal or seizure risk.